Relevant Publications:
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Carneiro, Sónia, Amaral, A.L., Veloso, A.C.A., Dias, T., Peres, A.M.,
Ferreira, E.C., Rocha, I. Assessment of physiological conditions in E.
coli fermentations by epifluorescent microscopy and image analysis.
Biotechnology Progress (in press)
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Veloso, A.C.A., Rocha, I., Ferreira, E.C. Monitoring of fed-batch E. coli
fermentations with software sensors. Bioprocess and Biosystems
Engineering (accepted)
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Rocha, M., Mendes, R., Maia, P., Pinto, J.P., Rocha, I., Ferreira, E.C.
Evaluating Simulated Annealing Algorithms in the Optimization of
Bacterial Strains. Lecture Notes in Artificial Intelligence,
4874, 473–484, 2007.
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Rocha, M., Pinto, J.P., Rocha, I., Ferreira, E.C.
Evaluating Evolutionary
Algorithms and Differential Evolution for the Online Optimization of
Fermentation Processes. Lecture Notes in Computer Science
4447, 236-246, 2007.
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Patil, K. R., Rocha, I., Forster, J.,
Nielsen, J. Evolutionary programming as a platform for in silico
metabolic engineering. BMC Bioinformatics 6:308, 2005.
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Rocha, I., Forster, J., Nielsen, J.; Design and application of
genome-scale reconstructed metabolic models. Gene Essentiality at
Genome scale: Protocols and Bioinformatics (A.L. Osterman, Gerdes,
S., Eds.). In series: Methods in Molecular Biology, Vol. 416, Ch.
29, 409-431, Humana Press 2008 (ISBN: 978-1-58829-378-7).
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Veloso, A.C.A, Rocha, I., Ferreira, E.C.
Identification of Yield Coefficients in an E. coli Model - an Optimal
Experimental Design Using Genetic Algorithms. Computer Applications
in Biotechnology 2004 (Pons, M.-N., Van Impe, J.F.M., eds.),
Elsevier, 43-48, 2005.
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Lubenova, V., Rocha,
I., Ferreira, E.C.
Estimation of Multiple Biomass Growth Rates and
Biomass Concentration in a Class of Bioprocesses. Bioprocess and
Biosystems Engineering 25:6, 395-406, 2003.
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Rocha,
I., Ferreira, E.C.,
On-line simultaneous monitoring of glucose and acetate with FIA
during high cell density fermentation of recombinant E. coli. Analytica
Chimica Acta, 462:2, 293-304, 2002.
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Model-based Strategies for Computer-Aided Process Operation of
Recombinant Human Protein Production. Phd Thesis, 2003.
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